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NOV/CCN3 induces cartilage protection by inhibiting PI3K/AKT/mTOR pathway

Osteoarthritis (OA), an age‐related degenerative joint disease, is pathologically characterized by articular cartilage degeneration and synovial inflammation. Nephroblastoma overexpressed (NOV or CCN3), a matricellular protein, is a primary member of the CCN family (Cyr61, Ctgf, NOV) of proteins and...

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Detalles Bibliográficos
Autores principales: Huang, Xiaojian, Ni, Bowei, Mao, Zekai, Xi, Yang, Chu, Xiangyu, Zhang, Rui, Ma, Xiaohu, You, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815824/
https://www.ncbi.nlm.nih.gov/pubmed/31454155
http://dx.doi.org/10.1111/jcmm.14621