A gain of function paradox: Targeted therapy for glioblastoma associated with abnormal NHE9 expression

Glioblastoma (GBM) is the most frequent and inevitably lethal primary brain cancer in adults. It is recognized that the overexpression of the endosomal Na(+)/H(+) exchanger NHE9 is a potent driver of GBM progression. Patients with NHE9 overexpression have a threefold lower median survival relative t...

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Detalles Bibliográficos
Autores principales: Pall, Ashley E., Juratli, Lena, Guntur, Dhyana, Bandyopadhyay, Krisanu, Kondapalli, Kalyan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815843/
https://www.ncbi.nlm.nih.gov/pubmed/31532058
http://dx.doi.org/10.1111/jcmm.14665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815843/
https://www.ncbi.nlm.nih.gov/pubmed/31532058
http://dx.doi.org/10.1111/jcmm.14665

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