Protection from Amyloid β Peptide–Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor

Recent imaging studies of amyloid and tau in cognitively normal elderly subjects imply that Alzheimer’s pathology can be tolerated by the brain to some extent due to compensatory mechanisms operating at the cellular and synaptic levels. The present study investigated the effects of an allosteric inh...

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Detalles Bibliográficos
Autores principales: Cui, Su-Ying, Yang, Ming-Xin, Zhang, Yong-He, Zheng, Victor, Zhang, Han-Ting, Gurney, Mark E., Xu, Ying, O’Donnell, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2019
Materias:
Neuropharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815937/
https://www.ncbi.nlm.nih.gov/pubmed/31488603
http://dx.doi.org/10.1124/jpet.119.259986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815937/
https://www.ncbi.nlm.nih.gov/pubmed/31488603
http://dx.doi.org/10.1124/jpet.119.259986

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