Tumor acidity activated triphenylphosphonium-based mitochondrial targeting nanocarriers for overcoming drug resistance of cancer therapy

The drug resistance in cancer treatment with DOX is mainly related to the overexpression of drug efflux proteins, residing in the plasma and nuclear membranes. Delivering DOX into the mitochondria, lacking drug efflux proteins, is an interesting method to overcome DOX resistance. To solve the proble...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Hui, Li, Jia-Mi, Deng, Kai, Zhou, Wei, Wang, Cai-Xia, Wang, Qian, Li, Kun-Heng, Zhao, Hong-Yang, Huang, Shi-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815947/
https://www.ncbi.nlm.nih.gov/pubmed/31660085
http://dx.doi.org/10.7150/thno.35748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815947/
https://www.ncbi.nlm.nih.gov/pubmed/31660085
http://dx.doi.org/10.7150/thno.35748

Ejemplares similares