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Rational design of caspase-responsive smart molecular probe for positron emission tomography imaging of drug-induced apoptosis
Purpose: Positron emission tomography (PET) imaging of apoptosis is very important for early evaluation of tumor therapeutic efficacy. A stimuli-responsive probe based on the peptide sequence Asp-Glu-Val-Asp (DEVD), [(18)F]DEVD-Cys(StBu)-PPG(CBT)-AmBF(3) ([(18)F]1), for PET imaging of tumor apoptosi...
Prif Awduron: | , , , , , , , , , |
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Fformat: | Online Erthygl Texto |
Iaith: | English |
Cyhoeddwyd: |
Ivyspring International Publisher
2019
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Pynciau: | |
Mynediad Ar-lein: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815954/ https://www.ncbi.nlm.nih.gov/pubmed/31660080 http://dx.doi.org/10.7150/thno.35084 |