Rational design of caspase-responsive smart molecular probe for positron emission tomography imaging of drug-induced apoptosis

Purpose: Positron emission tomography (PET) imaging of apoptosis is very important for early evaluation of tumor therapeutic efficacy. A stimuli-responsive probe based on the peptide sequence Asp-Glu-Val-Asp (DEVD), [(18)F]DEVD-Cys(StBu)-PPG(CBT)-AmBF(3) ([(18)F]1), for PET imaging of tumor apoptosi...

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Detalles Bibliográficos
Autores principales: Qiu, Ling, Wang, Wei, Li, Ke, Peng, Ying, Lv, Gaochao, Liu, Qingzhu, Gao, Feng, Seimbille, Yann, Xie, Minhao, Lin, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815954/
https://www.ncbi.nlm.nih.gov/pubmed/31660080
http://dx.doi.org/10.7150/thno.35084

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