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Genome landscapes of rectal cancer before and after preoperative chemoradiotherapy

Resistance to preoperative chemoradiotherapy (CRT) is a major obstacle to cancer treatment in patients with locally advanced rectal cancer. This study was to explore genome alterations in rectal cancer under CRT stress. Methods: Whole-exome sequencing (WES) was performed on 28 paired tumors collecte...

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Detalles Bibliográficos
Autores principales: Yang, Jie, Lin, Yuan, Huang, Ying, Jin, Jing, Zou, Shuangmei, Zhang, Xiaolong, Li, Hongmin, Feng, Ting, Chen, Jinna, Zuo, Zhixiang, Zheng, Jian, Li, Yexiong, Gao, Ge, Wu, Chen, Tan, Wen, Lin, Dongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815957/
https://www.ncbi.nlm.nih.gov/pubmed/31660073
http://dx.doi.org/10.7150/thno.37794