FKBP4 connects mTORC2 and PI3K to activate the PDK1/Akt-dependent cell proliferation signaling in breast cancer

Purpose: Among the FKBP family members, FKBP4 has been described to have a potential role in tumorigenesis, and as a putative tissue marker. We previously showed that FKBP4, an HSP90-associated co-chaperone, can elicit immune response as a tumor-specific antigen, and are overexpressed in breast canc...

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Detalles Bibliográficos
Autores principales: Mangé, Alain, Coyaud, Etienne, Desmetz, Caroline, Laurent, Estelle, Béganton, Benoit, Coopman, Peter, Raught, Brian, Solassol, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815969/
https://www.ncbi.nlm.nih.gov/pubmed/31660083
http://dx.doi.org/10.7150/thno.35561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815969/
https://www.ncbi.nlm.nih.gov/pubmed/31660083
http://dx.doi.org/10.7150/thno.35561

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