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Signaling Complexity Measured by Shannon Entropy and Its Application in Personalized Medicine

Traditional approaches to cancer therapy seek common molecular targets in tumors from different patients. However, molecular profiles differ between patients, and most tumors exhibit inherent heterogeneity. Hence, imprecise targeting commonly results in side effects, reduced efficacy, and drug resis...

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Detalles Bibliográficos
Autores principales: Conforte, Alessandra J., Tuszynski, Jack Adam, da Silva, Fabricio Alves Barbosa, Carels, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816034/
https://www.ncbi.nlm.nih.gov/pubmed/31695721
http://dx.doi.org/10.3389/fgene.2019.00930