Impact of statins on cellular respiration and de‐differentiation of myofibroblasts in human failing hearts

AIMS: Fibroblast to myofibroblast trans‐differentiation with altered bioenergetics precedes cardiac fibrosis (CF). Either prevention of differentiation or promotion of de‐differentiation could mitigate CF‐related pathologies. We determined whether 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A (HMG‐CoA) red...

Descripción completa

Detalles Bibliográficos
Autores principales: Emelyanova, Larisa, Sra, Amar, Schmuck, Eric G., Raval, Amish N., Downey, Francis X., Jahangir, Arshad, Rizvi, Farhan, Ross, Gracious R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816080/
https://www.ncbi.nlm.nih.gov/pubmed/31520523
http://dx.doi.org/10.1002/ehf2.12509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816080/
https://www.ncbi.nlm.nih.gov/pubmed/31520523
http://dx.doi.org/10.1002/ehf2.12509

Ejemplares similares