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Dynamic imaging of cellular pH and redox homeostasis with a genetically encoded dual-functional biosensor, pHaROS, in yeast

Intracellular pH and redox states are critical for multiple processes and partly determine cell behavior. Here, we developed a genetically encoded dual-function probe, named p H and redox-sensitive fluorescent protein (pHaROS), for simultaneous real-time detection of changes in redox potential and p...

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Detalles Bibliográficos
Autores principales: Zhao, Hang, Zhang, Yu, Pan, Mingming, Song, Yichen, Bai, Ling, Miao, Yuchen, Huang, Yanqin, Zhu, Xiaohong, Song, Chun-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816096/
https://www.ncbi.nlm.nih.gov/pubmed/31488545
http://dx.doi.org/10.1074/jbc.RA119.007557