Cross-species comparison of CAR-mediated procarcinogenic key events in a 3D liver microtissue model

Characterisation of the mode of action (MOA) of constitutive androstane receptor (CAR)-mediated rodent liver tumours involves measurement 5 key events including activation of the CAR receptor, altered gene expression, hepatocellular proliferation, clonal expansion and increased hepatocellular adenom...

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Detalles Bibliográficos
Autores principales: Plummer, Simon, Beaumont, Bobby, Wallace, Stephanie, Ball, Graeme, Wright, Jayne, McInnes, Liz, Currie, Richard, Peffer, Rich, Cowie, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816142/
https://www.ncbi.nlm.nih.gov/pubmed/31673501
http://dx.doi.org/10.1016/j.toxrep.2019.09.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816142/
https://www.ncbi.nlm.nih.gov/pubmed/31673501
http://dx.doi.org/10.1016/j.toxrep.2019.09.010

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