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Cross-species comparison of CAR-mediated procarcinogenic key events in a 3D liver microtissue model
Characterisation of the mode of action (MOA) of constitutive androstane receptor (CAR)-mediated rodent liver tumours involves measurement 5 key events including activation of the CAR receptor, altered gene expression, hepatocellular proliferation, clonal expansion and increased hepatocellular adenom...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816142/ https://www.ncbi.nlm.nih.gov/pubmed/31673501 http://dx.doi.org/10.1016/j.toxrep.2019.09.010 |