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Tumor vasculature remolding by thalidomide increases delivery and efficacy of cisplatin

BACKGROUND: A promising strategy to overcome the chemoresistance is the tumor blood vessel normalization, which restores the physiological perfusion and oxygenation of tumor vasculature. Thalidomide (Thal) has been shown to increase the anti-tumor effect of chemotherapy agents in solid tumors. Howev...

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Detalles Bibliográficos
Autores principales: Shen, Yanwei, Li, Shuting, Wang, Xin, Wang, Mengying, Tian, Qi, Yang, Jiao, Wang, Jichang, Wang, Biyuan, Liu, Peijun, Yang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816178/
https://www.ncbi.nlm.nih.gov/pubmed/31656203
http://dx.doi.org/10.1186/s13046-019-1366-x