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Tumor vasculature remolding by thalidomide increases delivery and efficacy of cisplatin
BACKGROUND: A promising strategy to overcome the chemoresistance is the tumor blood vessel normalization, which restores the physiological perfusion and oxygenation of tumor vasculature. Thalidomide (Thal) has been shown to increase the anti-tumor effect of chemotherapy agents in solid tumors. Howev...
Autores principales: | Shen, Yanwei, Li, Shuting, Wang, Xin, Wang, Mengying, Tian, Qi, Yang, Jiao, Wang, Jichang, Wang, Biyuan, Liu, Peijun, Yang, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816178/ https://www.ncbi.nlm.nih.gov/pubmed/31656203 http://dx.doi.org/10.1186/s13046-019-1366-x |
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