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Human Colonoid Monolayers to Study Interactions Between Pathogens, Commensals, and Host Intestinal Epithelium

Human 3-dimensional (3D) enteroid or colonoid cultures derived from crypt base stem cells are currently the most advanced ex vivo model of the intestinal epithelium. Due to their closed structures and significant supporting extracellular matrix, 3D cultures are not ideal for host-pathogen studies. E...

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Detalles Bibliográficos
Autores principales: In, Julie G., Foulke-Abel, Jennifer, Clarke, Elizabeth, Kovbasnjuk, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816237/
https://www.ncbi.nlm.nih.gov/pubmed/31033964
http://dx.doi.org/10.3791/59357