Optimization of a calcium-dependent Protein A-derived domain for mild antibody purification

As reported here, we developed and optimized a purification matrix based on a Protein A-derived domain, Z(Ca), displaying calcium-dependent antibody binding. It provides an alternative to the acidic elution conditions of conventional Protein A affinity chromatography for purification of sensitive an...

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Detalles Bibliográficos
Autores principales: Scheffel, Julia, Kanje, Sara, Borin, Jesper, Hober, Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816396/
https://www.ncbi.nlm.nih.gov/pubmed/31526164
http://dx.doi.org/10.1080/19420862.2019.1662690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816396/
https://www.ncbi.nlm.nih.gov/pubmed/31526164
http://dx.doi.org/10.1080/19420862.2019.1662690

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