Direct measurement of light and heavy antibody chains using ion mobility and middle-down mass spectrometry

The analysis of monoclonal antibodies (mAbs) by a middle-down mass spectrometry (MS) approach is a growing field that attracts the attention of many researchers and biopharmaceutical companies. Usually, liquid fractionation techniques are used to separate mAbs polypeptides chains before MS analysis....

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Detalles Bibliográficos
Autores principales: Melani, Rafael D., Srzentić, Kristina, Gerbasi, Vincent R., McGee, John P., Huguet, Romain, Fornelli, Luca, Kelleher, Neil L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816405/
https://www.ncbi.nlm.nih.gov/pubmed/31607219
http://dx.doi.org/10.1080/19420862.2019.1668226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816405/
https://www.ncbi.nlm.nih.gov/pubmed/31607219
http://dx.doi.org/10.1080/19420862.2019.1668226

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