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Does structurally-mature dengue virion matter in vaccine preparation in post-Dengvaxia era?

The unexpectedly low vaccine efficacy of Dengvaxia®, developed by Sanofi Pasteur, and a higher risk of severe diseases after vaccination among dengue-naive children or children younger than 6 years old, have cast skepticism about the safety of dengue vaccination resulting in the suspension of school...

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Detalles Bibliográficos
Autores principales: Galula, Jedhan Ucat, Salem, Gielenny M., Chang, Gwong-Jen J., Chao, Day-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816432/
https://www.ncbi.nlm.nih.gov/pubmed/31314657
http://dx.doi.org/10.1080/21645515.2019.1643676