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Emerging approaches to target mitochondrial apoptosis in cancer cells

Apoptosis is a highly conserved programme for removing damaged and unwanted cells. Apoptosis in most cells is coordinated on mitochondria by the Bcl-2 family of proteins. The balance between pro- and anti-apoptotic Bcl-2 family proteins sets a threshold for mitochondrial apoptosis, a balance that is...

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Detalles Bibliográficos
Autores principales: Gilmore, Andrew, King, Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816453/
https://www.ncbi.nlm.nih.gov/pubmed/31681471
http://dx.doi.org/10.12688/f1000research.18872.1