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Fragment-based screening with natural products for novel anti-parasitic disease drug discovery
Introduction: Fragment-based drug discovery can identify relatively simple compounds with low binding affinity due to fewer binding interactions with protein targets. FBDD reduces the library size and provides simpler starting points for subsequent chemical optimization of initial hits. A much great...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816479/ https://www.ncbi.nlm.nih.gov/pubmed/31512943 http://dx.doi.org/10.1080/17460441.2019.1653849 |