The phenanthrene derivative PJ34 exclusively eradicates human pancreatic cancer cells in xenografts

Recent reports demonstrate an exclusive eradication of a variety of human cancer cells by the modified phenanthridine PJ34. Their eradication during mitosis is attributed to PJ34 preventing NuMA clustering in the mitotic spindle poles of human malignant cells, which is crucial for their normal mitos...

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Detalles Bibliográficos
Autores principales: Visochek, Leonid, Atias, Dikla, Spektor, Itay, Castiel, Asher, Golan, Talia, Cohen-Armon, Malka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817443/
https://www.ncbi.nlm.nih.gov/pubmed/31692907
http://dx.doi.org/10.18632/oncotarget.27268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817443/
https://www.ncbi.nlm.nih.gov/pubmed/31692907
http://dx.doi.org/10.18632/oncotarget.27268

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