The predictive capability of immunohistochemistry and DNA sequencing for determining TP53 functional mutation status: a comparative study of 41 glioblastoma patients

Tumor protein 53 (p53) regulates fundamental pathways of cellular growth and differentiation. Aberrant p53 expression in glioblastoma multiforme, a terminal brain cancer, has been associated with worse patient outcomes and decreased chemosensitivity. Therefore, correctly identifying p53 status in gl...

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Detalles Bibliográficos
Autores principales: Roshandel, Aarash K., Busch, Christopher M., Mullekom, Jennifer Van, Cuoco, Joshua A., Rogers, Cara M., Apfel, Lisa S., Marvin, Eric A., Sontheimer, Harald W., Umans, Robyn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817445/
https://www.ncbi.nlm.nih.gov/pubmed/31692772
http://dx.doi.org/10.18632/oncotarget.27252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817445/
https://www.ncbi.nlm.nih.gov/pubmed/31692772
http://dx.doi.org/10.18632/oncotarget.27252

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