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Preclinical analysis of human mesenchymal stem cells: tumor tropism and therapeutic efficiency of local HSV-TK suicide gene therapy in glioblastoma

Glioblastoma are highly invasive and associated with limited therapeutic options and a grim prognosis. Using stem cells to extend current therapeutic strategies by targeted drug delivery to infiltrated tumors cells is highly attractive. This study analyzes the tumor homing and therapeutic abilities...

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Detalles Bibliográficos
Autores principales: Dührsen, Lasse, Hartfuß, Sophie, Hirsch, Daniela, Geiger, Sabine, Maire, Cecile L., Sedlacik, Jan, Guenther, Christine, Westphal, Manfred, Lamszus, Katrin, Hermann, Felix G., Schmidt, Nils Ole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817450/
https://www.ncbi.nlm.nih.gov/pubmed/31692882
http://dx.doi.org/10.18632/oncotarget.27071