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Preclinical analysis of human mesenchymal stem cells: tumor tropism and therapeutic efficiency of local HSV-TK suicide gene therapy in glioblastoma
Glioblastoma are highly invasive and associated with limited therapeutic options and a grim prognosis. Using stem cells to extend current therapeutic strategies by targeted drug delivery to infiltrated tumors cells is highly attractive. This study analyzes the tumor homing and therapeutic abilities...
Autores principales: | Dührsen, Lasse, Hartfuß, Sophie, Hirsch, Daniela, Geiger, Sabine, Maire, Cecile L., Sedlacik, Jan, Guenther, Christine, Westphal, Manfred, Lamszus, Katrin, Hermann, Felix G., Schmidt, Nils Ole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817450/ https://www.ncbi.nlm.nih.gov/pubmed/31692882 http://dx.doi.org/10.18632/oncotarget.27071 |
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