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Minocycline Ameliorates Depressive-Like Behavior and Demyelination Induced by Transient Global Cerebral Ischemia by Inhibiting Microglial Activation

Global cerebral ischemia (GCI) commonly occurs in the elderly. Subcortical white matter lesions and oligodendrocyte (OLG) loss caused by cerebral ischemia have been implicated in the development of post-ischemic depression and cognitive impairment. OLGs are necessary for axonal myelination; the disr...

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Detalles Bibliográficos
Autores principales: Du, Bingying, Li, Hailong, Zheng, Huiwen, Fan, Cunxiu, Liang, Meng, Lian, Yongjie, Wei, Zelan, Zhang, Yanbo, Bi, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817504/
https://www.ncbi.nlm.nih.gov/pubmed/31695615
http://dx.doi.org/10.3389/fphar.2019.01247