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Minocycline Ameliorates Depressive-Like Behavior and Demyelination Induced by Transient Global Cerebral Ischemia by Inhibiting Microglial Activation
Global cerebral ischemia (GCI) commonly occurs in the elderly. Subcortical white matter lesions and oligodendrocyte (OLG) loss caused by cerebral ischemia have been implicated in the development of post-ischemic depression and cognitive impairment. OLGs are necessary for axonal myelination; the disr...
Autores principales: | Du, Bingying, Li, Hailong, Zheng, Huiwen, Fan, Cunxiu, Liang, Meng, Lian, Yongjie, Wei, Zelan, Zhang, Yanbo, Bi, Xiaoying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817504/ https://www.ncbi.nlm.nih.gov/pubmed/31695615 http://dx.doi.org/10.3389/fphar.2019.01247 |
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