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Ancestry-Dependent Enrichment of Deleterious Homozygotes in Runs of Homozygosity
Runs of homozygosity (ROH) are important genomic features that manifest when an individual inherits two haplotypes that are identical by descent. Their length distributions are informative about population history, and their genomic locations are useful for mapping recessive loci contributing to bot...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817522/ https://www.ncbi.nlm.nih.gov/pubmed/31543216 http://dx.doi.org/10.1016/j.ajhg.2019.08.011 |