Cargando…

Simultaneous Determination of Five Alkaloids by HPLC-MS/MS Combined With Micro-SPE in Rat Plasma and Its Application to Pharmacokinetics After Oral Administration of Lotus Leaf Extract

An environment-friendly and efficient method for simultaneous determination of five alkaloids (nunciferine, O-nornuciferin, liriodenine, armepavine, and pronuciferine) in rat plasma was established by HPLC-MS/MS associated with micro-solid phase extraction (micro-SPE). The plasma sample was pretreat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zou, Shuhan, Ge, Yuanyuan, Chen, Xuanhao, Li, Jin, Yang, Xuejing, Wang, Hui, Gao, Xiumei, Chang, Yan-xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817585/ https://www.ncbi.nlm.nih.gov/pubmed/31695616 http://dx.doi.org/10.3389/fphar.2019.01252

Ejemplares similares

A Simple, Sensitive, and Reliable Method for the Simultaneous Determination of Multiple Antibiotics in Vegetables through SPE-HPLC-MS/MS
por: Feng, Yao, et al.
Publicado: (2018)

Profiling and Pharmacokinetic Studies of Alkaloids in Rats After Oral Administration of Zanthoxylum nitidum Decoction by UPLC-Q-TOF-MS/MS and HPLC-MS/MS
por: Huang, Aihua, et al.
Publicado: (2019)

Using the SPE and Micro-HPLC-MS/MS Method for the Analysis of Betalains in Rat Plasma after Red Beet Administration
por: Sawicki, Tomasz, et al.
Publicado: (2017)

Assessment of Tryptophan, Tryptophan Ethylester, and Melatonin Derivatives in Red Wine by SPE-HPLC-FL and SPE-HPLC-MS Methods
por: Fracassetti, Daniela, et al.
Publicado: (2019)

Development of an SPE–HPLC–MS method for simultaneous determination and pharmacokinetic study of bioactive constituents of Yu Ping Feng San in rat plasma after oral administration
por: Li, Tao, et al.
Publicado: (2013)

An Established HPLC-MS/MS Method for Evaluation of the Influence of Salt Processing on Pharmacokinetics of Six Compounds in Cuscutae Semen
por: Liu, Jiao, et al.
Publicado: (2019)

HPLC-ESI-MS/MS of Imidazole Alkaloids in Pilocarpus microphyllus
por: Sawaya, Alexandra CH F, et al.
Publicado: (2008)

Development of an HPLC-MS/MS Method for the Determination of Alkaloids in Lupins
por: Eugelio, Fabiola, et al.
Publicado: (2023)

New Method for Simultaneous Determination of Microcystins and Cylindrospermopsin in Vegetable Matrices by SPE-UPLC-MS/MS
por: Díez-Quijada, Leticia, et al.
Publicado: (2018)

Development and Validation of a HPLC-ESI-MS/MS Method for Simultaneous Quantification of Fourteen Alkaloids in Mouse Plasma after Oral Administration of the Extract of Corydalis yanhusuo Tuber: Application to Pharmacokinetic Study
por: Du, Weijuan, et al.
Publicado: (2018)

Development and Validation of a HPLC-MS/MS Method for Simultaneous Determination of Twelve Bioactive Compounds in Epimedium: Application to a Pharmacokinetic Study in Rats
por: Sun, Mengjie, et al.
Publicado: (2018)

Simultaneous Determination and Pharmacokinetic Study of Six Components in Rat Plasma by HPLC-MS/MS after Oral Administration of Acanthopanax sessiliflorus Fruit Extract
por: Du, Peng, et al.
Publicado: (2016)

Proteolytic Profiling of Streptococcal Pyrogenic Exotoxin B (SpeB) by Complementary HPLC-MS Approaches
por: Blöchl, Constantin, et al.
Publicado: (2021)

LC–MS/MS method for the quantitation of decitabine and venetoclax in rat plasma after SPE: Application to pharmacokinetic study
por: Alnasser, Abdulaziz I., et al.
Publicado: (2023)

Simultaneous Determination of Six Uncaria Alkaloids in Mouse Blood by UPLC–MS/MS and Its Application in Pharmacokinetics and Bioavailability
por: Chen, Lianguo, et al.
Publicado: (2020)

Green Extraction of Alkaloids and Polyphenols from Peumus boldus Leaves with Natural Deep Eutectic Solvents and Profiling by HPLC-PDA-IT-MS/MS and HPLC-QTOF-MS/MS
por: Torres-Vega, Jeniffer, et al.
Publicado: (2020)

Combining HPLC-DAD-QTOF-MS and HPLC-SPE-NMR to Monitor In Vitro Vitetrifolin D Phase I and II Metabolism
por: Sturm, Sonja, et al.
Publicado: (2021)

Pharmacokinetic and Bioavailability Studies of Galgravin after Oral and Intravenous Administration to Rats Using HPLC-MS/MS Method
por: Zhao, Lulu, et al.
Publicado: (2021)

Effect of processing on the alkaloids in Aconitum tubers by HPLC-TOF/MS()
por: Liu, Min, et al.
Publicado: (2017)

Pharmacokinetic Studies of Three Alkaloids in Rats After Intragastrical Administration of Lycopodii Herba Extract by LC-MS/MS
por: Ma, Dongke, et al.
Publicado: (2019)

Rapid and Simultaneous Quantification of Five Quinolizidine Alkaloids in Lupinus angustifolius L. and Its Processed Foods by UPLC–MS/MS
por: Hwang, In Min, et al.
Publicado: (2020)

SPE–UPLC–MS/MS for Determination of 36 Monomers of Alkylphenol Ethoxylates in Tea
por: Lin, Qin, et al.
Publicado: (2023)

Simultaneous Determination of Five Phenolic Acids and Four Flavonoid Glycosides in Rat Plasma Using HPLC-MS/MS and Its Application to a Pharmacokinetic Study after a Single Intravenous Administration of Kudiezi Injection
por: Shi, Peiying, et al.
Publicado: (2018)

Simultaneous determination of calycosin, prim-O-glucosylcimifugin, and paeoniflorin in rat plasma by HPLC-MS/MS: application in the pharmacokinetic analysis of HQCF
por: Gu, Yulong, et al.
Publicado: (2020)

Simultaneous Determination of Schisandrin and Promethazine with Its Metabolite in Rat Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study
por: Gao, Sijia, et al.
Publicado: (2019)

Simultaneous measurement of tadehaginoside and its principal metabolite in rats by HPLC–MS/MS and its application in pharmacokinetics and tissue distribution study
por: Zhang, Cai-Yun, et al.
Publicado: (2021)

Quantitative HPLC-MS analysis of nucleotide sugars in plant cells following off-line SPE sample preparation
por: Behmüller, Robert, et al.
Publicado: (2014)

Rhodoterpenoids A‒C, Three New Rearranged Triterpenoids from Rhododendron latoucheae by HPLC‒MS‒SPE‒NMR
por: Liu, Fei, et al.
Publicado: (2017)

Simultaneous Quantification and Pharmacokinetic Study of Five Homologs of Dalbavancin in Rat Plasma Using UHPLC-MS/MS
por: Zhu, Difeng, et al.
Publicado: (2020)

Amphetamines analysis in wastewaters - method performance of solid phase extraction - higher performance liquid chromatography mass spectrometry techniques (SPE-HPLC MS/MS)
por: Mustapha, Aliru Olajide, et al.
Publicado: (2011)

Simultaneous Evaluation of the Influence of Panax ginseng on the Pharmacokinetics of Three Diester Alkaloids after Oral Administration of Aconiti Lateralis Radix in Rats Using UHPLC/QQQ-MS/MS
por: Yang, Liang, et al.
Publicado: (2018)

Simultaneous Analysis of Anthocyanin and Non-Anthocyanin Flavonoid in Various Tissues of Different Lotus (Nelumbo) Cultivars by HPLC-DAD-ESI-MS(n)
por: Chen, Sha, et al.
Publicado: (2013)

2-Deoxyglucose and hydroxychloroquine HPLC-MS-MS analytical methods and pharmacokinetic interactions after oral co-administration in male rats
por: Sun, Dongxiao, et al.
Publicado: (2023)

Determination of fenticonazole in human plasma by HPLC–MS/MS and its application to pharmacokinetic studies()
por: Mao, Weixing, et al.
Publicado: (2017)

Determination of Puquitinib in Human Plasma by HPLC–ESI MS/MS: Application to Pharmacokinetic Study
por: Zhan, Jing, et al.
Publicado: (2018)

Evaluation of the Influence of Zhenwu Tang on the Pharmacokinetics of Digoxin in Rats Using HPLC-MS/MS
por: Li, Chao, et al.
Publicado: (2021)

A Sample and Sensitive HPLC-MS/MS Method for Simultaneous Determination of Ziyuglycoside I and Its Metabolite Ziyuglycoside II in Rat Pharmacokinetics
por: Li, Zhi-Feng, et al.
Publicado: (2018)

Simultaneous quantitation of folic acid and 5-methyltetrahydrofolic acid in human plasma by HPLC–MS/MS and its application to a pharmacokinetic study()
por: Zheng, Xiao-Hong, et al.
Publicado: (2015)

Pharmacokinetic and excretion study of three alkaloids in rats using UPLC-MS/MS after oral administration of menispermi rhizoma capsules
por: Yu, Jia, et al.
Publicado: (2018)

Simultaneous Determination of 21 Sulfonamides in Poultry Eggs Using Ionic Liquid-Modified Molecularly Imprinted Polymer SPE and UPLC–MS/MS
por: Suo, Decheng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_v9etpitqduaqvn1eskgfp8rcco