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TCR Fingerprinting and Off-Target Peptide Identification

Adoptive T cell therapy using patient T cells redirected to recognize tumor-specific antigens by expressing genetically engineered high-affinity T-cell receptors (TCRs) has therapeutic potential for melanoma and other solid tumors. Clinical trials implementing genetically modified TCRs in melanoma p...

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Detalles Bibliográficos
Autores principales: Karapetyan, Armen R., Chaipan, Chawaree, Winkelbach, Katharina, Wimberger, Sandra, Jeong, Jun Seop, Joshi, Bishnu, Stein, Robert B., Underwood, Dennis, Castle, John C., van Dijk, Marc, Seibert, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817589/
https://www.ncbi.nlm.nih.gov/pubmed/31695703
http://dx.doi.org/10.3389/fimmu.2019.02501