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TCR Fingerprinting and Off-Target Peptide Identification
Adoptive T cell therapy using patient T cells redirected to recognize tumor-specific antigens by expressing genetically engineered high-affinity T-cell receptors (TCRs) has therapeutic potential for melanoma and other solid tumors. Clinical trials implementing genetically modified TCRs in melanoma p...
Autores principales: | Karapetyan, Armen R., Chaipan, Chawaree, Winkelbach, Katharina, Wimberger, Sandra, Jeong, Jun Seop, Joshi, Bishnu, Stein, Robert B., Underwood, Dennis, Castle, John C., van Dijk, Marc, Seibert, Volker |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817589/ https://www.ncbi.nlm.nih.gov/pubmed/31695703 http://dx.doi.org/10.3389/fimmu.2019.02501 |
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