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Long and Repeat-Rich Intronic Sequences Favor Circular RNA Formation under Conditions of Reduced Spliceosome Activity

Circular RNAs (circRNAs), an important class of regulatory RNAs, have been shown to be the most prevalent in the brain compared with other tissues. However the processes governing their biogenesis in neurons are still elusive. Moreover, little is known about whether and how different biogenesis fact...

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Detalles Bibliográficos
Autores principales: Wang, Mantian, Hou, Jingyi, Müller-McNicoll, Michaela, Chen, Wei, Schuman, Erin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817660/
https://www.ncbi.nlm.nih.gov/pubmed/31590076
http://dx.doi.org/10.1016/j.isci.2019.08.058