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Resectable lung lesions malignancy assessment and cancer detection by ultra-deep sequencing of targeted gene mutations in plasma cell-free DNA

BACKGROUND: Early detection of lung cancer to allow curative treatment remains challenging. Cell-free circulating tumour (ct) DNA (ctDNA) analysis may aid in malignancy assessment and early cancer diagnosis of lung nodules found in screening imagery. METHODS: The multicentre clinical study enrolled...

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Detalles Bibliográficos
Autores principales: Peng, Muyun, Xie, Yuancai, Li, Xiaohua, Qian, Youhui, Tu, Xiaonian, Yao, Xumei, Cheng, Fangsheng, Xu, Feiyue, Kong, Deju, He, Bing, Liu, Chaoyu, Cao, Fengjun, Yang, Haoxian, Yu, Fenglei, Xu, Chuanbo, Tian, Geng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817693/
https://www.ncbi.nlm.nih.gov/pubmed/30981987
http://dx.doi.org/10.1136/jmedgenet-2018-105825