Viral Infections Exacerbate FUS-ALS Phenotypes in iPSC-Derived Spinal Neurons in a Virus Species-Specific Manner

Amyotrophic lateral sclerosis (ALS) arises from an interplay of genetic mutations and environmental factors. ssRNA viruses are possible ALS risk factors, but testing their interaction with mutations such as in FUS, which encodes an RNA-binding protein, has been difficult due to the lack of a human d...

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Detalles Bibliográficos
Autores principales: Bellmann, Jessica, Monette, Anne, Tripathy, Vadreenath, Sójka, Anna, Abo-Rady, Masin, Janosh, Antje, Bhatnagar, Rajat, Bickle, Marc, Mouland, Andrew J., Sterneckert, Jared
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817715/
https://www.ncbi.nlm.nih.gov/pubmed/31695598
http://dx.doi.org/10.3389/fncel.2019.00480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817715/
https://www.ncbi.nlm.nih.gov/pubmed/31695598
http://dx.doi.org/10.3389/fncel.2019.00480

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