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Review: The bile acids urso- and tauroursodeoxycholic acid as neuroprotective therapies in retinal disease

Bile acids are produced in the liver and excreted into the intestine, where their main function is to participate in lipid digestion. Ursodeoxycholic acid (UDCA) and tauroursodeoxycholic acid (TUDCA) have shown antiapoptotic, anti-inflammatory, and antioxidant effects in various models of neurodegen...

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Detalles Bibliográficos
Autores principales: Daruich, Alejandra, Picard, Emilie, Boatright, Jeffrey H., Behar-Cohen, Francine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817734/
https://www.ncbi.nlm.nih.gov/pubmed/31700226