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Conformational flexibility of adenine riboswitch aptamer in apo and bound states using NMR and an X-ray free electron laser
Riboswitches are structured cis-regulators mainly found in the untranslated regions of messenger RNA. The aptamer domain of a riboswitch serves as a sensor for its ligand, the binding of which triggers conformational changes that regulate the behavior of its expression platform. As a model system fo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817744/ https://www.ncbi.nlm.nih.gov/pubmed/31606878 http://dx.doi.org/10.1007/s10858-019-00278-w |