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Urinary metabolomics reveals kynurenine pathway perturbation in newborns with transposition of great arteries after surgical repair
INTRODUCTION: Transposition of the great arteries (TGA) is a cyanotic congenital heart defect that requires surgical correction, with the use of cardiopulmonary-bypass (CPB), usually within 3 weeks of life. The use of CPB in open heart surgery results in brain hypoperfusion and in a powerful systemi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817811/ https://www.ncbi.nlm.nih.gov/pubmed/31659512 http://dx.doi.org/10.1007/s11306-019-1605-3 |