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Rare variants in non-coding regulatory regions of the genome that affect gene expression in systemic lupus erythematosus
Personalized medicine approaches are increasingly sought for diseases with a heritable component. Systemic lupus erythematosus (SLE) is the prototypic autoimmune disease resulting from loss of immunologic tolerance, but the genetic basis of SLE remains incompletely understood. Genome wide associatio...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817816/ https://www.ncbi.nlm.nih.gov/pubmed/31659207 http://dx.doi.org/10.1038/s41598-019-51864-9 |