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Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced
Insulin deficiency in type 1 diabetes (T1D) is generally considered a consequence of immune‐mediated specific beta‐cell loss. Since healthy pancreatic islets consist of ~65% beta cells, this would lead to reduced islet size, while the number of islets per pancreas volume (islet density) would not be...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817830/ https://www.ncbi.nlm.nih.gov/pubmed/31493350 http://dx.doi.org/10.1002/cjp2.140 |