No more helper adenovirus: production of gutless adenovirus (GLAd) free of adenovirus and replication-competent adenovirus (RCA) contaminants

Gene therapy is emerging as an effective treatment option for various inherited genetic diseases. Gutless adenovirus (GLAd), also known as helper-dependent adenovirus (HDAd), has many notable characteristics as a gene delivery vector for this particular type of gene therapy, including broad tropism,...

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Detalles Bibliográficos
Autores principales: Lee, Dongwoo, Liu, Jida, Junn, Hyun Jung, Lee, Eun-Joo, Jeong, Kyu-Shik, Seol, Dai-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817846/
https://www.ncbi.nlm.nih.gov/pubmed/31659156
http://dx.doi.org/10.1038/s12276-019-0334-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817846/
https://www.ncbi.nlm.nih.gov/pubmed/31659156
http://dx.doi.org/10.1038/s12276-019-0334-z

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