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Proteome and Secretome Dynamics of Human Retinal Pigment Epithelium in Response to Reactive Oxygen Species

Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries, and is characterized by slow retinal degeneration linked to chronic reactive oxygen species (ROS) in the retinal pigmented epithelium (RPE). The molecular mechanisms leading to RPE dysfunction in respons...

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Detalles Bibliográficos
Autores principales: Meyer, Jesse G., Garcia, Thelma Y., Schilling, Birgit, Gibson, Bradford W., Lamba, Deepak A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817852/
https://www.ncbi.nlm.nih.gov/pubmed/31659173
http://dx.doi.org/10.1038/s41598-019-51777-7