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Proteome and Secretome Dynamics of Human Retinal Pigment Epithelium in Response to Reactive Oxygen Species
Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries, and is characterized by slow retinal degeneration linked to chronic reactive oxygen species (ROS) in the retinal pigmented epithelium (RPE). The molecular mechanisms leading to RPE dysfunction in respons...
Autores principales: | Meyer, Jesse G., Garcia, Thelma Y., Schilling, Birgit, Gibson, Bradford W., Lamba, Deepak A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817852/ https://www.ncbi.nlm.nih.gov/pubmed/31659173 http://dx.doi.org/10.1038/s41598-019-51777-7 |
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