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Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system
Diabetes has become one of the major noninfectious diseases that seriously endanger public health. The formation of islet amyloid polypeptide (IAPP) affects the normal physiological functions of the body, such as glucose metabolism and lipid metabolism. The mature human IAPP protein (hIAPP) has a st...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817862/ https://www.ncbi.nlm.nih.gov/pubmed/31659151 http://dx.doi.org/10.1038/s41419-019-2056-5 |