Biochemical and Structural Insights Concerning Triclosan Resistance in a Novel YX(7)K Type Enoyl-Acyl Carrier Protein Reductase from Soil Metagenome

Enoyl-acyl carrier protein reductase (ENR) catalyzes the last reduction step in the bacterial type II fatty acid biosynthesis cycle. ENRs include FabI, FabL, FabL2, FabK, and FabV. Previously, we reported a unique triclosan (TCL) resistant ENR homolog that was predominant in obligate intracellular p...

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Detalles Bibliográficos
Autores principales: Khan, Raees, Zeb, Amir, Choi, Kihyuck, Lee, Gihwan, Lee, Keun Woo, Lee, Seon-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817880/
https://www.ncbi.nlm.nih.gov/pubmed/31659200
http://dx.doi.org/10.1038/s41598-019-51895-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817880/
https://www.ncbi.nlm.nih.gov/pubmed/31659200
http://dx.doi.org/10.1038/s41598-019-51895-2

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