Cargando…

Ribosomal protein uL3 targets E2F1 and Cyclin D1 in cancer cell response to nucleolar stress

Several experimental strategies in the treatment of cancer include drug alteration of cell cycle regulatory pathways as a useful strategy. Extra-ribosomal functions of human ribosomal protein L3 (uL3) may affect DNA repair, cell cycle arrest and apoptosis. In the present study, we demonstrated that...

Descripción completa

Detalles Bibliográficos
Autores principales: Pecoraro, Annalisa, Carotenuto, Pietro, Russo, Giulia, Russo, Annapina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817900/
https://www.ncbi.nlm.nih.gov/pubmed/31659203
http://dx.doi.org/10.1038/s41598-019-51723-7