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Ribosomal protein uL3 targets E2F1 and Cyclin D1 in cancer cell response to nucleolar stress
Several experimental strategies in the treatment of cancer include drug alteration of cell cycle regulatory pathways as a useful strategy. Extra-ribosomal functions of human ribosomal protein L3 (uL3) may affect DNA repair, cell cycle arrest and apoptosis. In the present study, we demonstrated that...
Autores principales: | Pecoraro, Annalisa, Carotenuto, Pietro, Russo, Giulia, Russo, Annapina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817900/ https://www.ncbi.nlm.nih.gov/pubmed/31659203 http://dx.doi.org/10.1038/s41598-019-51723-7 |
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