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Effect of HIF‐1α/miR‐10b‐5p/PTEN on Hypoxia‐Induced Cardiomyocyte Apoptosis

BACKGROUND: Few reports have addressed the mechanism by which microRNA miR‐10b‐5p regulates post–myocardial infarction (post‐MI) cardiomyocyte apoptosis under hypoxic conditions. METHODS AND RESULTS: C57BL/6 mice underwent surgical ligation of the left anterior descending artery to create an MI or i...

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Detalles Bibliográficos
Autores principales: Wu, Liping, Chen, Yafen, Chen, Yuanyuan, Yang, Wenbo, Han, Yanxin, Lu, Lin, Yang, Ke, Cao, Jiumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818010/
https://www.ncbi.nlm.nih.gov/pubmed/31480879
http://dx.doi.org/10.1161/JAHA.119.011948