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Stimulation of Collateral Vessel Growth by Inhibition of Galectin 2 in Mice Using a Single‐Domain Llama‐Derived Antibody

BACKGROUND: In the presence of arterial stenosis, collateral artery growth (arteriogenesis) can alleviate ischemia and preserve tissue function. In patients with poorly developed collateral arteries, Gal‐2 (galectin 2) expression is increased. In vivo administration of Gal‐2 inhibits arteriogenesis....

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Detalles Bibliográficos
Autores principales: Hollander, Maurits R., Jansen, Matthijs F., Hopman, Luuk H. G. A., Dolk, Edward, van de Ven, Peter M., Knaapen, Paul, Horrevoets, Anton J., Lutgens, Esther, van Royen, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818022/
https://www.ncbi.nlm.nih.gov/pubmed/31594443
http://dx.doi.org/10.1161/JAHA.119.012806