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Targeting Extracellular Heat Shock Protein 70 Ameliorates Doxorubicin‐Induced Heart Failure Through Resolution of Toll‐Like Receptor 2–Mediated Myocardial Inflammation

BACKGROUND: Heart failure (HF) is one of the most significant causes of morbidity and mortality for the cardiovascular risk population. We found previously that extracellular HSP70 (heat shock protein) is an important trigger in cardiac hypertrophy and fibrosis, which are associated with the develop...

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Detalles Bibliográficos
Autores principales: Liu, Peng, Bao, Hua‐Yan, Jin, Cai‐Cai, Zhou, Ji‐Chao, Hua, Fang, Li, Ke, Lv, Xiao‐Xi, Cui, Bing, Hu, Zhuo‐Wei, Zhang, Xiao‐Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818050/
https://www.ncbi.nlm.nih.gov/pubmed/31576776
http://dx.doi.org/10.1161/JAHA.119.012338