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GILT restricts the cellular entry mediated by the envelope glycoproteins of SARS-CoV, Ebola virus and Lassa fever virus

Interferons (IFNs) control viral infections by inducing expression of IFN-stimulated genes (ISGs) that restrict distinct steps of viral replication. We report herein that gamma-interferon-inducible lysosomal thiol reductase (GILT), a lysosome-associated ISG, restricts the infectious entry of selecte...

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Detalles Bibliográficos
Autores principales: Chen, Danying, Hou, Zhifei, Jiang, Dong, Zheng, Mei, Li, Guoli, Zhang, Yue, Li, Rui, Lin, Hanxin, Chang, Jinhong, Zeng, Hui, Guo, Ju-Tao, Zhao, Xuesen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818130/
https://www.ncbi.nlm.nih.gov/pubmed/31631785
http://dx.doi.org/10.1080/22221751.2019.1677446